Seventy percent of the chronic myeloid leukaemic patients can be cured with stem cell transplantations. As I described in my earliest posts, stem cells are cells that proliferate and give rise to all the other blood cells. Earlier stem cell transplantation was widely used but now it has reduced due to the success rate of therapy with imatinib.
Compared to treatment with imatinib, stem cell transplantation has a risk of death due to graft versus host reaction or due to opportunistic infections. Therefore, your physician will weigh the risks upon benefits and decide the most suitable treatment.
You are more likely to have problems with stem cell transplantation, if you belong to any of the following categories.
· Older age
· Time of transplantation is delayed even if the disease was diagnosed earlier.
The histocompatibility with the donor is poor.
References : Kumar P and Clark M, 2009. Clinical Medicine. 7th ed.
References : Kumar P and Clark M, 2009. Clinical Medicine. 7th ed.
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